心血管介入治疗中造影剂肾病防治的研究进展

Research Progress in Contrast-induced Nephropathy in Cardiovascular Intervention

造影剂肾病是应用造影剂后的一种急性肾损伤,目前是院内急性肾衰竭的第3大病因,造影剂所造成的危害日益引起医学界的关注。造影剂肾病的防治手段包括术前停止使用肾毒性药物、严格掌握造影适应证、合理使用对比剂、水化治疗等,常用药物有N-乙酰半胱氨酸、腺苷受体抑制剂、他汀类药物等。现就近几年造影剂肾病的防治方法予以综述。

Contrast-induced nephropathy（CIN）is an acute renal injury secondary to the use of contrast media,as the third cause of nosocomial acute renal failure.The threats posed by contrast media are increasingly attended by clinicians.The prophylactic measures of CIN include the termination of nephrotoxic drugs,strict indication of use,appropriate use of contrast media,and rehydration.The commonly used drugs consist of N-acetylcysteine,adenosine receptor inhibitor,and statins.This article reviews the prophylactic measures of CIN.