川崎病126例临床分析

Clinical Analysis of 126 Cases of Atypical Kawasaki Disease

目的探讨川崎病(KD)的临床特征,尤其是不典型KD的临床特征及早期诊断。方法对平谷区医院儿科1999年1月至2009年1月诊治的126例患儿的临床资料进行回顾性分析和总结。结果不典型KD具备诊断标准6条中2条者1例,占3.33%(1/30);具备3条者13例,占43.33%(13/30);具备4条者16例,占53.33%(16/30)。冠状动脉受累者共26例,30例不典型KD中冠状动脉受累者共10例。结论不典型KD冠脉损害率高,临床表现虽不完全符合诊断标准,但通过临床仔细观察,结合实验室检查及超声心动图均能获得早期诊断,使患儿得到及时治疗。

Objective To investigate the clinical features and early diagnosis for atypical Kawasaki disease（KD）.Methods A total of 126 patients with KD hospitalized in department of pediatrics,Beijing Pinggu district hospital from Jan 1999 to Jan 2009 were analyzed.Results 1 atypical KD case meeting 2 main symptoms,counted for 3.33%（1/30）;13 cases meeting 3 main symptoms,counted for 43.33%（13/30）;6 cases meeting 4 main symptoms,counted for 53.33%（16/30）.Totally 26 cases were complicated with coronary artery lesions of KD,10 cases were complicated with coronary artery lesions of atypical KD.Conclusion Atypical KD coronary damage rate was high,clinical manifestation was not completely according with diagnostic criteria,but through careful clinical observation,combining laboratory examination and echocardiographic,all can get early diagnosis,children can get timely treatment.