头顶一棵珠抗炎镇痛作用的实验研究

Study on Anti-inflammatory and Analgesic Effect of Tschoskii Maxim

目的:探讨头顶一棵珠的抗炎镇痛作用。方法:抗炎实验采用二甲苯致小鼠耳廓肿胀等常规抗炎模型;镇痛实验采用热板法和醋酸扭体法。结果:头顶一棵珠提取物可明显抑制二甲苯致小鼠耳廊肿胀及蛋清引起的大鼠足跖肿胀,能显著抑制大鼠棉球肉芽肿的增重及醋酸致小鼠扭体反应,可明显延长热板引起小鼠疼痛反应的痛阈值。结论:富硒头顶一棵珠有明显的抗炎镇痛作用。

Objective： To study the anti-inflammatory and analgesic effects of Tschoskii Maxim.Methods： A few conventional models,such as the mouse pinna swelling induced by xylene;Analyesia experiments adopted hot-plate procedure and torsion body method.Results： Tschoskii Maxim obviously inhibited the swelling of mouse pinna induced by xylene,suppressed the edema of rat hind paw elicited by egg white,significantly depressed the increase of proliferation of granuloma led by implanting wtton pellet and the torsion boby of rats.It had an abatement effect of algesin induced by heat with tail flick method.Condusion： Tschoskii Maxim is an effective medicine on anti-inflammatory.