餐后血脂异常与缺血性脑卒中的关系

The relationship between postprandial dyslipidemia and ischemic stroke

目的观察餐后血脂异常与缺血性脑卒中的关系。方法选择缺血性脑卒中患者158例(脑卒中组),同期健康体检者160例(对照组)。对2组体重指数、C反应蛋白、血脂、血糖、血压进行比较,并用回归分析研究缺血性脑卒中的危险因素。结果与对照组比较,脑卒中组体重指数、C反应蛋白、TC、LDL-C、VLDL、空腹血糖、血压明显升高,HDL-C明显降低;脑卒中组餐后4 h TG和HDL-C明显高于空腹TG和HDL-C;多元回归分析,缺血性脑卒中与餐后4 h TG相关。结论餐后血脂异常可能是导致缺血性脑卒中的重要因素。

Objective To investigate the relationship between postprandial dyslipidemia and ischemic stroke. Methods 158 patients with ischemic stroke served as stroke group and 160 healthy people selected from the Health Care Department served as control group. Body mass index,CRP, blood lipids, blood glucose and blood pressure were compared between the 2 groups and regression analysis was used to analyze risk factors for stroke. Results Compared with the control group, body mass index, CRP, TC, LDL-C, VLDL, fasting blood glucose and blood pressure increased sig- nificantly while HDL-C decreased significantly in stroke group. The TG and HDL-C 4 h after meal were significantly higher than fasting TG and HDL-C in stroke group. Multiple regression analy- sis showed that ischemic stroke was correlated with4 h postprandial TG. Conclusion The postprandial dyslipidemia may be the important factor leading to ischemic stroke.