摘要
目的了解降钙素原在全身炎症反应综合征(SIRS)中的变化及与病情危重程度的关系。方法选择2007年4月—2009年6月我院儿科SIRS患儿80例,并将80例患儿依据简化小儿危重症评分(PCIS)分为3组,非危重组54例,危重组20例,极危重组6例。选择同期健康儿童20例作为对照组。采用快速半定量降钙素原(PCT)试纸条测PCT的质量浓度。结果 SIRS患儿血清PCT质量浓度高于对照组(χ2=18.86P,=0.00),细菌感染血清PCT浓度高于病毒感染组及非感染组(χ2=28.57P,=0.00χ;2=20.48P,=0.00)。病毒感染组与非感染组PCT质量浓度无显著性差异(χ2=0.25P,=0.617)。SIRS患儿血清PCT质量浓度与简化PICS评分呈显著负相关(r=-0.793P,=0.00)。结论 PCT可作为鉴别细菌感染与病毒感染的敏感指标,PCT水平的高低可反映病情的严重程度。
Objective To explore the change of PCT in SIRS and the relationship between PCT and children＇s condition.Methods 80 children with SIRS from April 2007 to June 2009 were randomly according to Pediatric Critical Illness were divided into three groups： non-serious group（54 cases）,serious group（20 cases）and very serious group（6 cases）.The concentration of PCT was detected by rapid semi-quantitative PCT test strip.Results The serum level of PCT in children with SIRS was higher than that in the control group（χ2=18.86,P=0.00）.The serum level of PCT in children with bacterial infection was significantly higher than that in children with virus infection and non-infectious（χ2=28.57,P=0.00,χ2=20.48,P=0.00）.The serum level of PCT in children with virus infection and non-infectious was no significant difference（χ2=0.25,P=0.617）.There was significant negative correlation between the serum level of PCT in children with SIRS and the PCIS score（r=-0.793,P=0.00）.Conclusion PCT can be used as a sensitive indicator to indentify bacterial infection and virus infection.The level of PCT may reflect the severity of the disease and it is beneficial to judge the disease.
出处
《基层医学论坛》
2011年第1期29-30,共2页
The Medical Forum
