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基因芯片数据多尺度分析的y~n曲线模型

y~n Curve Model of Multi-scale Analysis to DNA Microarray Data
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摘要 针对离散的基因芯片表达数据难以进行系统分析的问题,提出基因芯片数据的y~n曲线模型,将基因芯片数据转化为唯一的一列信号,从而可以对其进行多尺度分析。对人类胎儿脑发育过程中大脑皮质基因表达基于y~n曲线模型进行小波多尺度降噪,结果证明,y~n曲线的降噪效果比用基因芯片原始数据更好。 The model of y-n curve is set up to solve the problem that discrete gene chip data are difficult to be systematically analyzed, which makes the data be changed into a row of sole signal, and can be studied by multi-scale analysis. Results of denoising the cerebral cortex gene expression of developing human brain based on wavelet multi-scale analysis show that the denoised effect of y-n curve is better than that of raw data.
出处 《计算机工程》 CAS CSCD 北大核心 2011年第2期20-21,24,共3页 Computer Engineering
基金 国家自然科学基金资助项目"基因时空表达信息多尺度分析方法研究"(30872184)
关键词 基因芯片 y^n曲线 多尺度分析 DNA microarray y-n curve mu|ti-scale analysis
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