胺碘酮与利多卡因对室性心动过速的疗效对比研究

Comparison Effect Research of Amidarone and Lidocaine on Ventricular Tachycardia

目的对比胺碘酮和利多卡因对室性心动过速的治疗效果及各自的副反应。方法对我院住院的55例室性心动过速患者随机分成胺碘酮和利多卡因治疗组,胺碘酮组给予胺碘酮150mg～300 mg静注,利多卡因组给予利多卡因100mg～200mg静注。结果胺碘酮和利多卡因对室性心动过速的治疗效果差异无统计学意义,但副作用利多卡因较胺碘酮高（P〈0.05）。结论室性心动过速应首选胺碘酮,利多卡因可作为一线药物,主要用于QT间期延长所致的室性心动过速,但要注意其不良反应。

Objective To compare the effects of amiodarone and lidocaine on ventricular tachycardia.Methods Fifty-five patients with ventricular tachycardia were randomly divided into two groups,treated with amiodarone 150-300mg or lidocaine 100-200mg.Results Both amiodarone and lidocaine were effective in completely suppressing ventricular tachycardia,but lidocaine had more adverse effects（p0.05）.Conclusion Amiodarone may be a more attractive choice among patients with ventricular tachycardia,,And lidocaine is mostly used on ventricular tachycardia caused by long O-T,also its adverse effects should be attentioned.