摘要
慢性心力衰竭患者常伴有贫血,大量的研究证实红细胞刺激生成因子及铁剂的治疗可以改善此类患者的预后,但对于部分高内源性促红细胞生成素水平,即存在促红细胞生成素抵抗的患者缺乏大规模的临床研究。红细胞分布宽度的增加和血色素的下降、炎性因子增加、铁代谢的损害存在相关性,但红细胞分布宽度在心力衰竭伴贫血患者中的诊断及治疗意义待进一步的明确。
Patients with chronic heart failure are frequently anemic.Past data has shown that treatment with erythropoietin and iron compounds can improve the patient＇s prognosis.However,there no large scale clinical research has been done on the treatment of patients with high endogenous erythropoietin level.Increasing red blood cell distribution width（RDW） correlated with decreasing hemoglobin,increasing inflammatory factor,and impaired iron mobilization,but evidence indicating the treatment value of RDW in heart failure with anemia is lacking.
出处
《心血管病学进展》
CAS
2011年第1期98-100,共3页
Advances in Cardiovascular Diseases
关键词
慢性心力衰竭
贫血
促红细胞生成素
红细胞分布宽度
铁剂
chronic heart failure
anemia
erythropoietin
red blood cell distribution width
iron compounds
