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T波电交替的研究进展 被引量：6

Current Status of T-wave Alternans
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摘要 T波电交替是指在规整的心律时,体表心电图上T波形态、极性和振幅出现逐搏交替变化的现象,其与恶性室性心律失常以及心脏性猝死的发生有着极为密切的联系。T波电交替的检测方法有频域分析和时域分析方法两种。临床试验证实,T波电交替对恶性室性心律失常事件的预测价值与有创的电生理检测价值相似。但微伏级T波电交替检测作为一种无创的检测手段,其对于发生各种致死性心脏病危险分级的作用仍需要临床实验进一步研究证实,现就T波电交替的发生机制、临床意义以及发展现状等进行综述。 T-wave alternans（TWA）,the beat-to-beat fluctuation in T wave amplitude and morphology,is closely linked to vulnerability to ventricular arrhythmias in various experimental and clinical conditions.Clinically,TWA is most commonly measured using the spectral method and time-domain methods.With current instrumentation and detecting condition,TWA represents an inexpensive,convenient,non-invasive testing modality.The future role of TWA testing in non-invasive risk stratification of fatal heart diseases is awaiting results of ongoing clinical trials.This article presents the mechanism,clinical indications,and research status of TWA according to current literature.
作者 任莉娜 齐国先
机构地区 中国医科大学附属第一医院心内科
出处 《心血管病学进展》 CAS 2011年第1期107-111,共5页 Advances in Cardiovascular Diseases
关键词 T波电交替 猝死 危险分层 心电描记术 T-wave alternans sudden cardiac death risk stratification electrocardiography
分类号 R541.7 [医药卫生—心血管疾病]
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参考文献23

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  • 2Salemo-Uriarte JA, de Ferrari GM, Klersy C ,et al. Prognostic value of T-wave ahemans in patients with heart failure due to nonischemic cardiomyopathy: re- suits of the ALPHA Study[ J ]. J Am Coll Cardiol,2007,50(19) :1896-1904.
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同被引文献57

  • 1杨瑞红.心源性猝死的预测及相关危险因素分析[J].中国心血管病研究,2005,3(1):62-63. 被引量：16
  • 2庞文跃,孙英贤,耿宁,刘兴利,马淑梅,李晓东,胡大一.T波电交替预测老年急性心肌梗死患者早期室颤的作用[J].中国老年学杂志,2005,25(9):1021-1023. 被引量：8
  • 3刘燕,张云飞,姜荣建.高血压左室肥厚致心律失常机制的探讨[J].现代中西医结合杂志,2006,15(5):685-686. 被引量：10
  • 4刘元生,李毅刚.自主神经与QT间期[J].临床心电学杂志,2006,15(1):9-10. 被引量：14
  • 5Hennersdorf MG, Niebch V, Perings C, et al. T wave alternans and ventricular arrhythmias in arterial hypertension. Hypertension, 2001,37(2) :199-203.
  • 6钟杭美.动态心电图预警心脏性猝死[J].临床心电学杂志,2007,16(5):352-355. 被引量：18
  • 7Van der Avoort C J,Filion K B,DendukuriN. Microvolt T-wa ve alternans as a predictor of mortality and severe arrhythmias in patients with left-ventricular dysfunction:a systematic review and meta-analysis[J].BMC Cardiovascular Disorders,2009.5.
  • 8Narayan S M. T-wave alternans and the susceptibility to ventricular arrhythmias[J].Journal of the American College of Cardiology,2006,(02):269.doi:10.1016/j.jacc.2005.08.066.
  • 9Wilson L D,Rosenbaum D S. Mechanisms of arrythmogenic cardiac alternans[J].Europace:European Pacing,Arrhythmias and Cardiac Electrophysiology,2007,(Suppl 6):vi77.
  • 10Costantini O,Rosenbaum D S,Hohnloser S H. The altemans before cardioverter defibr-illator (ABCD) Trial:a noninvasive strategy for primary prevention of sudden cardiac death using T-wave altemans[J].Journal of the American College of Cardiology,2009,(06):471.doi:10.1016/j.jacc.2008.08.077.

引证文献6

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心血管病学进展
2011年 第1期

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