甲型H1N1流感轻症326例临床特征分析

Clinical report of 326 cases infected with influenza A(H1N1)

目的总结2009年甲型H1N1流感发病和中西医治疗规律。方法对北京地坛医院2009年5月15日至8月2日收治的经核酸检测阳性的甲型H1N1流行性感冒患者326例进行回顾性病例分析。结果调查时段内以输入性病例为主,高发人群是青少年,占81.3%,病情温和。主要症状是发热、咳嗽、咽痛等。其中医病因病机是风热疫毒侵袭肺卫,共有131例采用单纯中医药治疗,在退热、核酸阴转时间等方面与抗病毒药奥司他韦疗效相当。结论治疗轻型甲型H1N1流感病例可单纯使用中医药,奥司他韦应用于高危或病情较重人群。

Objective This study aimed to summarize the clinic features and the therapeutical rule of influenza A（H1N1）on Chinese and Western medicine.Method 326 patients with influenza A（H1N1）confirmed by laboratory testing and treated in Beijing Ditan Hospital from 2009-5-15 to 2009-8-2 were taken into this retrospective study.Result In this study,more than half of the patients were the input cases,and the majority of the patients were adolescent.The process of the new type influenza seemed to be gentle.The usual symptoms included fever,cough and sore throat.In Chinese medicine,the pathogen of this disease belongs to wind-heat evil and the main pathogenesis is wind-heat evil attacking the lung and disturbing the defensive qi.Between the group treated by Chinese medicine and the group treated by antiviral drug（oseltamivir）,the time of defervescence and virus elimination were similar.Conclusion The influenza A（H1N1）patients without severe symptoms and influenza related complications can be treated by Chinese medicine singly.The antiviral drug should be used only in the patients with severe influenza related complications and the patients with high risk of severe influenza related complications.