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Advances of Bioinformatics Tools Applied in Virus Epitopes Prediction 被引量:7

Advances of Bioinformatics Tools Applied in Virus Epitopes Prediction
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摘要 In recent years,the in silico epitopes prediction tools have facilitated the progress of vaccines development significantly and many have been applied to predict epitopes in viruses successfully. Herein,a general overview of different tools currently available,including T cell and B cell epitopes prediction tools,is presented. And the principles of different prediction algorithms are reviewed briefly. Finally,several examples are present to illustrate the application of the prediction tools. In recent years,the in silico epitopes prediction tools have facilitated the progress of vaccines development significantly and many have been applied to predict epitopes in viruses successfully. Herein,a general overview of different tools currently available,including T cell and B cell epitopes prediction tools,is presented. And the principles of different prediction algorithms are reviewed briefly. Finally,several examples are present to illustrate the application of the prediction tools.
作者 Simon Rayner
出处 《Virologica Sinica》 SCIE CAS CSCD 2011年第1期1-7,共7页 中国病毒学(英文版)
基金 The National Natural Science Foundations of China (30870131) the National Key Projects in the Infectious Fields (2008ZX10002-011, 2008ZX10004-004)
关键词 EPITOPE BIOINFORMATICS Epitope prediction algorithms 预测工具 表位预测 病毒抗原 生物信息学 应用 B细胞表位 预测算法 T细胞
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