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瑞格列奈联合二甲双胍治疗新诊断2型糖尿病的疗效观察 被引量:24

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摘要 2型糖尿病初期β细胞功能受损主要表现为早时相胰岛素分泌的受损。近期研究发现,早时相胰岛素分泌在维持正常血糖稳定起重要作用,早期胰岛素分泌功能缺失则可导致餐后高血糖。因此,在糖尿病发生的早期阶段,应用一些改善早时相胰岛素分泌的药物,可有效降糖及保护胰岛功能。瑞格列奈(诺和龙)是一种新型促胰岛素分泌的药物,起效快,作用时间短;较传统磺脲类药物能更好地改善早时相分泌,从而控制餐时血糖的增高,
出处 《临床荟萃》 CAS 2011年第3期242-244,共3页 Clinical Focus
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