摘要
目的探讨扩张型心肌病(DCM)患者合并左心室附壁血栓的超声心动图特征。方法回顾性分析188例DCM患者超声心动图资料,根据左心室有无血栓形成分为无血栓组和有血栓组,对两组患者的超声心动图检查结果进行比较。结果血栓组共18例(9.6%),与无血栓组相比,该组患者左心室射血分数(LVEF)及左心室短轴缩短率(LVFS)较低,(28.9±9.8)%vs(36.4±6.6)%(、11.3±3.3)%vs(17.1±5.2)%,左心房内径(LAD)及左心室收缩末期内径(LVIDs)较大,(48.6±4.1)mm vs(43.2±5.1)mm、(61.7±4.7)mm vs(51.8±5.3)mm;中重度二尖瓣反流(MR)发生率较低(22.2%vs 70.5%,均P<0.01)。结论 DCM患者LAD及LVIDs较大、左心室心肌收缩力下降明显者易导致左心室附壁血栓形成;二尖瓣中重度MR有对抗左心室血栓形成的作用。
Objective To investigate the echocardiographic characters of left ventricular thrombus in patients with dilated cardiomyopathy(DCM).Methods We analyzed the data of 188 patients with DCM.The patients were divided into two groups:patients with left ventricle thrombus group and patients without left ventricle thrombus group.We sought to compare the transthoracic echocardiographic outcome of these two groups.Results We identified 18 patients(9.6%) with left ventricle thrombus.There were significant statistical difference in some factors between two groups,such as left ventricle ejection fraction(28.9±9.8)% vs(36.4±6.6)%,fractional shortening(11.3±3.3)% vs(17.1±5.2)%,internal diameter of systolic left ventricle(61.7±4.7)mm vs(51.8±5.3) mm,and left atrium(48.6±4.1) mm vs(43.2±5.1) mm(P0.01).Moderate-severe mitral valve regurgitation(22.2% vs 70.5%)more frequently occurred among patients without left ventricle thrombus(P0.01).Conclusion Our findings suggest that some factors may indicate a higher risk of thrombus formation,such as the left ventricular systolic disfunction,enlargement of internal diameter of systolic left ventricle and left atrium.Moderate-severe mitral valve regurgitation may prevent mural thrombus formation within the left ventricle.
出处
《临床荟萃》
CAS
2011年第4期296-297,300,F0002,共4页
Clinical Focus