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胃癌雌激素受体α、β与孕激素受体mRNA的表达及意义 被引量:2

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摘要 目的观察胃癌雌激素受体(ER)α、β及孕激素受体(PR)mRNA的表达,并探讨其意义。方法采用Sybr green荧光定量PCR法检测30例胃癌组织ERα、β及PR的mRNA表达,观察不同病理预后因素与其表达的关系。结果胃癌组织中ERα、β及PR mRNA表达水平分别为1.948±2.905、1.477±1.367、5.520±8.430,以PRmRNA为最高。低分化腺癌及分化程度低的胃癌组织ERβmRNA表达高(P均<0.05)。ERαmRNA、PR mRNA与病理类型及分化程度无相关关系。结论 ERβmRNA的表达差异与胃癌的病理类型和分化程度有关。
出处 《山东医药》 CAS 北大核心 2011年第1期33-34,共2页 Shandong Medical Journal
基金 上海长征医院三重三优优秀青年后备人才培养项目
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参考文献6

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二级参考文献19

共引文献14

同被引文献36

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