500例脑卒中患者代谢综合征各组分的分布调查研究

Investigation on the distribution of the components of metabolic syndrome in 500 cases of stroke

目的 探讨脑卒中与代谢综合征（MS）各组分之间的关系,为脑卒中及MS的预防提供科学理论依据.方法 脑卒中合并MS患者500例,根据人院时患者MS的不同组分及代谢异常情况分型.测量并记录全部受试者的收缩压（SBP）、舒张压（DBP）、空腹血糖（FPG）、血清甘油三酯（TG）、血清总胆固醇（TC）、血清低密度脂蛋白胆固醇（LDL-C）、血清高密度脂蛋白胆固醇（HDL-C）.结果 脑卒中合并MS患者以60～69岁人居多（39.60%）,且不存在性别差异（χ2=4.030,P=0.545）;在MS各组分中,高血压与脑卒中的相关性最强;不同组分组合的MS与脑卒中的关系分析表明,高血糖＋高血压＋高血脂组合患者在脑卒中合并MS患者中所占比例更大（48.00%,240/500）.结论 MS及其各组分都是影响脑卒中发病的重要因素,且MS组分在个体聚集越多的患者在脑卒中并发MS患者中所占比例越大.有针对性地干预MS各组分代谢异常情况对MS和脑卒中有重要防治作用.

Objective To explore the relation of stroke and metabolic syndrome （MS）, and provide theoretical evidence for prevention of stroke and MS. Methods Five hundred stroke patients accompanied with MS were enrolled, and divided into different types according to the distribution of the components of metabolic syndrome and abnormal metabolic condition. The systolic blood pressure（SBP） ,diastolic blood pressure（ DBP）,fasting glycemia （ FPG ）, triglycerides （ TG ）, total cholesterol （ TC ）, low density density lipoprotern-cholesterol （LDL-C）, high density density lipoprotern-cholesterol （HDL-C）of each patient were detected and recorded. Results Among these stroke patients with MS, most patients were 60 - 69 years old （ 39.60% ）, and there was no significant difference between two gender（ P = 0. 545 ）. Among each component of MS, hypertension was most related to MS;patients complicated with hypertension ＋ hyperlipidemia ＋ hyperglycemia were the most major proportion of stroke patients with MS（48. 00% ）. Conclusion MS and its components are all risk factors for stroke,and the more complication the patients had,the more patients suffered from stroke with MS. Targeted interventions of different type of abnormal condition has important prevention effect on MS and stroke.