期刊文献+

预防房颤患者的脑卒中:进展和争议 被引量:7

下载PDF
导出
摘要 房颤的首要治疗目标是预防卒中以及改善症状,临床上有采用恢复窦性节律或者控制心室率两种不同的治疗策略。由于患者特点以及对于心律失常的耐受性存在较大的差异,对房颤的治疗往往存在较大的挑战性。许多新的非常有希望替代华法林的药物如阿哌沙班、利伐沙班、达比加群酯、Tecarfarin等安全性、有效性、性价比的研究正在进行中。而安全性是左心耳封堵治疗在临床推广的最大障碍。心房颤动消融技术发展很快,但应用受到技术和费用的限制,尤其是术后患者的房颤负荷的评价以及对于远期疗效影响尚待观察。
作者 吴明
机构地区 海南省人民医院
出处 《海南医学》 CAS 2011年第3期2-7,共6页 Hainan Medical Journal
  • 相关文献

参考文献28

  • 1Wolf PA, Dawber TR, Thomas HE Jr, et al. Epidemiologic assess- ment of chronic atrial fibrillation and risk of stroke: the Framing- ham study [J]. Neurology, 1978, 28(10): 973-977.
  • 2Furberg CD, Psaty BM, Manolio TA, et al. Prevalence of atrial fi- brillation in elderly subjects (the Cardiovascular Health Study) [J]. Am J Cardiol, 1994, 74(3): 236-241.
  • 3Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation: a major con- tributor to stroke in the elderly. The Framingham Study [J]. Arch In- tern Med, 1987, 147(9):1561-1564.
  • 4Fatkin D, Kelly RP, Feneley MP. Relations between left atrial ap- pendage blood flow velocity, spontaneous echoeardiographie con- trast and thromboembolic risk in vivo [J]. J Am Coll Cardiol, 1994, 23(4): 961-969.
  • 5Black IW, Chesterman CN, Hopkins AP, et al. Hematologic corre- lates of left atria1 spontaneous echo contrast and thromboembolism in nonvalvular atrial fibrillation [J]. J Am Coll Cardiol, 1993, 21(2): 451-457.
  • 6Kamiyama N. Expression of cell adhesion molecules and the appear- ance of adherent leukocytes on the left atrial endothelium with atrial fibrillation: rabbit experimental model [J]. Jpn Circ J, 1998, 62(11): 837-843.
  • 7Diener HC. Stroke prevention using the oral direct thrombin inhibi- tor ximelagatran in pat- ients with nonvatvular atrial fibrillation. Pooled analysis from the SPORTIF Ⅲ and Ⅴ studies [J]. Cerebro- vasc Dis, 2006, 21: 279-293.
  • 8Petersen P, Grind M, Adler J, et al. Ximelagatran verses warfarin for stroke prevention in patients with nonvalvular atrial fabrillationL SPORTIF Ⅱ:a dose-guiding, tolerability and safety study [J]. J Am Cardiol, 2003, 41: 1445-1451.
  • 9Connolly S J, Ezekowitz MD, Yusuf S, et al. Dabigatran versus War- farin in Patients with Atrial Fibrillation [J]. N Engl J Med, 2009, 361: 1139-1151.
  • 10于忠.2009欧洲心脏病学会(ESC)参会报道[J].心脑血管病防治,2009,9(6):421-421. 被引量:10

共引文献9

同被引文献81

引证文献7

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部