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实验性糖尿病大鼠视网膜毛细血管变化规律Ⅱ.超微结构观察 被引量:1

REGULARITY OF MORPHOLOGICAL CHANGES OF RETINAL COPILLARIES IN EXPERIMENTAL DIABETIC RATS Ⅱ ULTRASTRUCTRAL OBSERVATION
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摘要 应用透射电镜观察STZ糖尿病大鼠视网膜毛细血管病变规律,发现病程1个月只见周细胞和内皮细胞核异染色质聚集靠边;病程3个月,周细胞和内皮细胞异染色质聚集靠边严重,毛细血管扩张,基底膜增厚;病程6个月,以上变化呈现加重趋势,毛细血管由扩张转为狭窄、变形、甚至闭塞。 This study carried out ultrastructral observations of retinal capillaries of STZ diabetic rats by transmissin electron microscope The results are as follows In diabetes one month(DM1),there were only nuclear metachromatin of pericytes and endothelial cells getting together and keeping to the side In DM3 nuclear metachromatin of pericytes and endothelial cell collected and kept to side gravely,capillaries expanded and increased in basement membrane In DM6,above-mentioned changes became progressively serious,but capillaries became narrow,deformed,even occluded
出处 《锦州医学院学报》 CAS 1999年第2期1-5,共5页 Journal of Jinzhou Medical College
关键词 糖尿病 毛细血管 基底膜 视网膜病变 大鼠 diabetic retinopathy capillary basement membrane transmission electron microscope
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