医学院校教职工脂肪肝横断面研究

Cross-sectional Survey of Fatty Liver Among Staff of a Medical College

目的了解医学院校教职工脂肪肝患病率,探讨脂肪肝患病率的影响因素,为脂肪肝的防治提供理论依据。方法收集该医学院校教职工体检结果,进行横断面调查。结果体检人数715人,可用于分析700人,脂肪肝总患病率34.70%,男性为43.80%,女性为26.30%。不同年龄组、不同性别脂肪肝患病率差异有统计学意义;单因素分析显示,高空腹血糖(FBG)、高血清总胆固醇(TC)、高甘油三酯(TG)、高血压、高血尿酸(UA)、高低密度脂蛋白胆固醇(LDL-C)、体质指数(BMI)增高是脂肪肝发生的可能危险因素,Logistic回归分析显示,性别、高TG、高血压、高LDL-C、BMI增高是脂肪肝发生的可能危险因素,OR值(95%CI)分别为1.576(1.055～2.354)、3.069(2.013～4.681)、1.877(1.124～3.136)、1.722(1.032～2.874)、7.275(4.613～11.475)。结论该医学院校教职工脂肪肝患病率处于较高水平。脂肪肝发生与BMI、TG、高血压、LDL-C、性别联系密切。

Objective To investigate the prevalence rate of fatty liver among the staff of a medical college,to explore the influencing factors of fatty liver,and to provide a theoretical basis for the prevention of fatty liver. Method A cross-sectional survey of physical examination results was conducted in the staff of a medical college. Results Data from 700 out of 715 staff members were analyzed.The prevalence rates of fatty liver in the overall staff,men,and women were 34.70%,43.80% and 26.30%,respectively.There were statistically significant differences in the prevalence rate of fatty liver among different age groups and between different genders.The results from the single factor analysis showed that the increasing of fasting blood glucose（FBG）,serum total cholesterol l（TC）,triglyceride（TG）,blood serum uric acid（UA）,low density lipoprotein cholesterol（LDL-C）,hypertension and high body mass index（BMI） were the possible risk factors of fatty liver.The results from the Logistic regression analysis showed that sex,the increasing of TG,hypertension,the increasing of LDL-C,and high BMI were the possible risk factors of fatty liver and OR（95%CI） was 1.576（1.055～2.354）,3.069（2.013～4.681）,1.877（1.124～3.136）,1.722（1.032～2.874） and 7.275（4.613～11.475）,respectively. Conclusions The prevalence rate of fatty liver in the staff members of the medical college was high.Fatty liver is closely related to BMI,TG,hypertension,LDL-C and sex.