不同性别冠心病患者血管病变程度的比较分析

Comparative analysis vascular lesions for patients with coronary heart disease by gender

目的研究不同性别的需行PCI的冠心病患者的血管病变严重程度,旨在为不同性别的冠心病患者采取行之有效的二级预防措施提供循证医学证据。方法选择已成功施行PCI手术的262例冠心病患者,对患者的常见的危险因素严格测量评估,根据患者不同血管病变严重程度的危险因素进行分组比较。结果研究结果显示,在侵犯病变血管男性和女性几乎一致,而在病变严重程度二者更是趋于一致。不同性别冠心病患者血管病变严重程度LM、LAD、LCX和RCA男性分别为25(11.8%)、176(83.4%)、105(49.8%)和148(70.1%),女性患者为6(11.8%)、43(84.3%)、22(43.1%)、36(70.6%);构成比比较男女患者无差别,差异无显著意义,P>0.05。结论研究结果提示,尽管女性患者比男性患者需行支架植入大约推迟5年,而且随着年龄增长,二者病变血管和血管病变严重程度并无区别,而女性患者随着年龄增长,患高血压的病人比男性患者多;高密度脂蛋白胆固醇(HDL-C)可能是女性患者的保护因素。

Objective To study the severity of blood vessels for coronary heart disease needs PCI by different gender, and to take effective secondary preventive measures and provide medical evidence for patients with coronary heart disease. Method 262 patients with coronary heart disease was successfully implemented by PCI and compared with the severity of vascular lesions by patients＇ gender. Result The results showed that blood vessels invasion for men and women were almost identical. The severity of coronary heart disease patients by different gender of LM, LAD, LCX and RCA of male were 25 （11.8%）, 176（83.4%）, 105 （49.8%） and 148 （70. 1%）, female patients were 6 （11.8%）, 43 （84.3%）, 22 （43.1%） and 36（70. 6%） ,posed no difference in male and female patients,P〉 0.05, no significant. Conclusion The results suggested that the female patients required stents was 5 years delayed than male patients, the severity of vascular increased with age, high-density lipoprotein cholesterol might be the protective factor in female patients, even women with high risk blood pressure in patients.