莫西沙星的严重不良反应及其防范

Severe Adverse Drug Reactions Induced by Moxifloxacin and Their Prevention

目的:提示临床高度关注莫西沙星的不良反应。方法:检索我院不良反应监测系统,对其中莫西沙星产生的3例严重不良反应报告进行分析。结果:3例莫西沙星严重不良反应中,暴发性肝衰竭1例,经抢救无效死亡;过敏性休克2例,经抢救未产生严重后果。结论:临床应重视莫西沙星严重不良反应的危害性。

OBJECTIVE：To prompt the adverse drug reactions （ADR） of moxifloxacin should be paid high attention to clinic. METHODS： Retrieved from ADR reporting and monitoring system of our hospital, 3 serious ADR cases induced by moxifloxacin were analyzed. RESULTS： Among 3 serious ADR cases induced by moxifloxacin, one case developed fulminant hepatic failure leading to death after rescue, and other 2 patients with anaphylactic shock was recovered without severe consequence after rescue. CONCLUSION：Great importance should be attached to ADR induced by moxifloxacin in the clinic.