《药典临床用药须知·中药卷》(2005年版)中含反药药对成方制剂收载情况与分析

Formulas containing couplet medicinal of incompatible medicinal recorded in Instructions of China Pharmacopoeia Application·Chinese medicine Volume(Edition 2005)

"十八反""十九畏"作为中药配伍禁忌的代名词,被历代医家所崇信,但反药配伍同用的文献记载及临床报道也屡见不鲜,因此反药配伍实质一直是众多学者研究的热点。《中华人民共和国药典临床用药须知》是《中华人民共和国药典》的配套丛书之一,是我国医药工作人员准确了解和合理使用《中华人民共和国药典》中各类药品的必备参考用书,其中亦收载含反药药对的成方制剂。2005年版《中华人民共和国药典临床用药须知.中药卷》共收载中成药品种1 423个,其中含反药药对的成方制剂共18个,包括含十八反药对的成方9个,含十九畏药对的成方9个。从以上成方反药药对的出现次数及成方制剂的功能主治、剂型用法、处方药味等方面进行归纳分析,为探讨反药配伍的临床使用规律提供思路,为指导临床合理安全使用十八反、十九畏药对提供借鉴。

The concepts of eighteen incompatible medicinal and nineteen medicinal of mutual antagonism are the synonym for prohibited combination of Chinese medicinal,which have been believed by physicians of all times.There were,however,literature and clinical records about contrary medicinal used together in formula designing,and the essential of combination of contrary medicinal has been a focus study.Instructions of China Pharmacopoeia Application is one of assorted series of China National Pharmacopoeia and has being indispensable reference for Chinese medical workers in reasonable administration of all types of medicinal,which records the formulas containing couplet medicinal of incompatible medicinal.Instructions of China Pharmacopoeia Application·Chinese medicine Volume（Edition 2005） records totally 1 423 patent formulas,among them there are 18 formulas containing couplet medicinal of incompatible medicinal including 9 containing couplet medicinal of eighteen incompatible medicinal and 9 containing couplet medicinal of nineteen medicinal of mutual antagonism.The frequency of couplet medicinal of contrary medicinal in above-mentioned formulas was analysed,and the functions,dosage forms,usages and ingredients of these formulas were summarized in the paper aiming at studying the usage laws of contrary medicinal combination in clinical practice and guiding reasonable application of eighteen incompatible medicinal and nineteen medicinal of mutual antagonism.