11，Gavg R,Yusuf S.Overview of randomized trial of angiotensin -converting enzyme inhibitors on mortality and morbidity in patients with heart failure.Collaborative Group on ACE inhibitors.JAMA,1995;273(18):1450
22，CIBIS-Ⅱ Investigators and Committees.The cardiac insufficiency bisoprolol study Ⅱ(CIBIS-Ⅱ)a randomised trial.Lancet,1999;353(9146):9
33，MERIT-HF Study Group.Effect of metoprolol CR/XL in chronic heart failure:Metoprolol CR/XL Randomised Intervention Trial in congestive Heart Failure(MERIT-HF).Lancet,1999;353(9169):2001
4Bauersachs J, Galuppo P, Fraccarollo D, et al. Improvement of left ventricular remodeling and function by hydroxymethylglutaryl coenzyme A reductase inhibition with cerivastatin in rats with heart failure after myocardial infarction [J]. Circulation, 2001
5Hayashidani S, Tsutsui H, Shiomi T, et al. Fluvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, attenuates left ventricular remodeling and failure after experimental myocardial infarction [J]. Circulation, 2002, 105:868
6Patel R, Nagueh SF, Tsybouleva N, et al. Simvastatin induces regression of cardiac hypertrophy and fibrosis and improves cardiac function in a transgenic rabbit model of human hypertrophic cardiomyopathy [J]. Circulation, 2001,104:317
7Laufs U, La Fata V, Plutzky J, et al. Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors [J]. Circulation, 1998, 97:1129.
8Oi S, Haneda T, Osaki J, et al. Lovastatin prevents angiotensin II-induced cardiac hypertrophy in cultured neonatal rat heart cells [J]. Eur J Pharmacol, 1999, 376:139
9Luo JD, Zhang WW, Zhang GP, et al. Simvastatin inhibits cardiac hypertrophy and angiotensin-converting enzyme activity in rats with aortic stenosis [J]. Clin Exp Pharmacol Physiol, 1999, 26:903
10Dechend R, Fiebeler A, Park JK, et al. Amelioration of angiotensin II-induced cardiac injury by a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor [J]. Circulation, 2001,104:576
