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Th1/Th2检测对肺炎、肺癌的诊断意义

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摘要 目的:比较肺炎患者、肺癌患者的外周血中Th1/Th2 细胞比例差异,从而进一步探讨Th1/Th2 细胞参与的免疫反应可能.方法:选取肺炎患者和初诊肺癌患者,采集35例诊断肺炎患者、35例肺癌患者和20例健康查体人员的外周血,采用流式细胞术检测Th1/Th2细胞的比例, 对三组间患者Th1 /Th2的比例进行统计分析.结果:初诊肺癌患者组外周血中Th1细胞比例低于肺炎患者组( P〈 0.05);而Th2细胞比例高于肺炎患者(P〈 0. 05).结论:外周血中CD4+辅助性T淋巴细胞亚群Th1, Th2的监测,可辅助肺炎和肺癌的鉴别诊断.Th1 /Th2细胞免疫平衡在肺炎患者中以Th1细胞免疫占优势为主,在肺癌患者中以Th2细胞免疫占优势为主.
机构地区 北京
出处 《医学信息(下旬刊)》 2011年第1期61-62,共2页 Medical information
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参考文献5

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