^(99)Tc^m-葡萄糖二酸亲肿瘤显像剂的动物实验

THE ANIMAL EXPERIMENT OF 99 Tc m\|GLUCARATE

选用９９ Ｔｃｍ 葡萄糖二酸（９９ Ｔｃｍ ｇｌｕｃａｒａｔｅ，简称９９ Ｔｃｍ ｇｌｕ）作为肿瘤阳性示踪剂，对肺腺癌小鼠模型进行动物实验。以主要组织器官的放射性摄取百分比及 Ｔ／ Ｎ Ｔ 作为统计指标并常规静态及延时显像观察。结果表明肿瘤组织对９９ Ｔｃｍ ｇｌｕ 有较好的摄取，延时 ６ ｈ 肿瘤摄取量达到最高。表明９９ Ｔｃｍ ｇｌｕ具有作为亲肿瘤显像剂的潜力。

A myocardiac infraction imaging reagent, 99 Tc\+m glucarate is injected into lung cancer of mice model to imaging. The primary results show that the tumor can uptake rather more 99 Tc m\|glucarate than the others. The uptake of 99 Tc m\|glucarate in tumor is the highest at 6 hours after injection. Evidently, the 99 Tc m\|glucarate is a hopeful tumor reagent.