摘要
本文采用多核细胞检测法（ＣＢ法），研究了６０Ｃｏ γ射线照射离体人血所诱发的体细胞ＨＰＲＴ基因位点的突变频率。实验结果表明，０～５０ Ｇｙ γ射线可诱发ＨＰＲＴ基因位点突变，ＨＰＲＴ基因位点突变的频率随照射剂量增加而升高，突变频率Ｙ（１０－ ３） 与照射剂量Ｄ（Ｇｙ）间可拟合为Ｙ＝
The frequency of HPRT site mutation induced in vitro by 60 Co γ rays in human blood cells and its dose effect relationship were investigated using a more simple, rapid and sensitive polynuclear cell assay. The results show that the frequency of HPRT site mutation induced by 0~5.0 Gy of γ rays was significantly higher than that for control. The frequency of HPRT site mutation is increased lineally with doses and could be represented in a lineal model Y =0 903+0 869 D . (
出处
《辐射防护》
CAS
CSCD
北大核心
1999年第6期466-469,共4页
Radiation Protection
