薏苡仁油抗肝癌的药理作用与临床应用

Pharmacological action and clinical application of anti-hepatoma of Coicis Semen oil

药理实验和临床研究证明薏苡仁油具有抗肝癌作用,其作用机制是诱导肝癌细胞凋亡,抑制癌细胞增殖;抑制肿瘤组织内血管形成,减少营养物质供应,抑制肿瘤生长;提高机体对肿瘤的免疫功能。薏苡仁油可以单用或者联合用药治疗原发性肝癌,薏苡仁油与化疗药联用治疗肝癌,能减弱化疗药引起的免疫功能低下和骨髓抑制的不良反应,具有良好的开发前景。

Pharmacological experiments and clinical researches suggest that Coicis Semen oil has certain anti-hepatoma effects.Its anti-hepatoma mechanism are：inhibiting hepatoma cells proliferation by inducing apoptosis,reducing nutritive supplies for growing tumor by inhibiting angiopoiesis in tumor tissue,increasing immunologic function against tumors.In the treatment of primary liver carcinoma,single Coicis Semen oil can be used,and Coicis Semen oil can also be combined with other medicines.If combined with chemotherapeutic drugs,it can decrease the incurrence of immune degeneration and bone marrow inhibition.Therefore,it has great potential for development.