妊娠期高血压疾病患者肝肾功能变化研究

Study on Liver and Kidney Function Changes in Patients with Gestational Hypertension

目的:研究和了解妊娠期高血压患者在妊娠期间的肝肾功能变化情况。方法:本文采用日立7080全自动生化分析仪检测总蛋白、白蛋白、谷丙转氨酶、谷草转氨酶和碱性磷酸酶肝功能指标和尿素氮、肌酐、尿酸几项肾功能指标。结果:疾病组总蛋白、白蛋白均低于正常组,而谷丙转氨酶、谷草转氨酶、碱性磷酸酶、尿素氮、肌酐和尿酸均高于正常组。肝肾功能指标两组间比较差异均有统计学意义(P<0.05,P<0.01)。结论:通过了解妊娠期高血压患者在妊娠期间的肝肾功能情况,提高警惕孕妇因为肝肾功能在一定程度上的变化而引起的疾病,并针对这些变化,适当采取保护患者肝肾功能或选择适宜时机终止妊娠等措施。

Objective：To research and understand the liver and kidney function changes in patients with gestational hypertension.Methods：Total protein,albumin,alanine aminotransferase,aspartate aminotransferase,and alkaline phosphatase in liver function and blood urea nitrogen,creatinine,uric acid in renal function were analyzed by Hitachi 7080 automatic biochemical analyzer.Results：In disease group,the total protein and albumin were lower than normal group.Alanine aminotransferase,aspartate aminotransferase,alkaline phosphatase,urea nitrogen,creatinine and uric acid were higher than normal group.There were statistically significant differences in liver and kidney function parameters between the two groups（P〈0.05,P〈0.01）. Conclusion：By understanding the liver and kidney function changes in patients with gestational hypertension during pregnancy, we should raise our guard on the disease caused by the changes of liver and kidney function in pregnant women,and to be appropriate to protect the liver and kidney function or to choose the appropriate time to terminate the pregnancy.