两种检测急性冠脉综合征患者CKMB及CTNI方法一致性分析被引量：2

Analysis on the consistency of two kinds of test for acute coronary syndrome

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摘要目的:评价急性冠脉综合征患者中,化验室心肌酶及标志物分析法检测心肌肌酸激酶同工酶(CKMB)和心肌肌钙蛋白I(CTNI)结果与心梗三联床旁检测法是否一致及其一致性程度。方法:对78例临床诊断急性冠脉综合征的患者同时采集两份标本,分别应用化验室心肌酶及标志物分析法和心梗三联床旁检测法进行CKMB及CTNI测定。采用配对卡方检验(McNemar Test)和一致性检验(Kappa检验)方法进行统计学分析。结果:两种方法测得CKMB和CTNI值比较差异无统计学意义(t=1.123,P=0.265;t=-0.326,P=0.747),且一致性较好(Kappa=0.579,P<0.05;Kappa=0.546,P<0.05)。采用配对卡方检验结果显示,两种方法测得CKMB和CTNI值升高程度差异均无统计学意义(P>0.05)。结论:化验室心肌酶及标志物分析法与心梗三联床旁检测法检测CKMB及CTNI值结果一致性较好。 Objective： We use myocrdium zymogram and myocardial trigeminy,two kinds of tests to diagnose acute coronary syndrome（ACS） at the same time.Compare the results of the two kinds of tests to see the consistency of them.Methods： To do myocardium zymogram and myocardial trigeminy at the same time for the patients with acute coronary syndrome（ACS）.Measurement data was recorded as mean ± standard error,numeration data was recorded as percentage constituent ratio;T test for numeration data comparasion,McNemar Test and Kappa Test for grouped data consistency analysis.Kappa value 0.75,indicated very good consistency,0.4≤Kappa≤0.75 indicated good consistency,Kappa 0.4 poor consistency.Results： The CKMB and CTNI values in the two kinds of tests had no significant differences（t=1.123,P=0.265;t=-0.326,P=0.747） and had good consistency（Kappa=0.579,P0.05;Kappa=0.546,P0.05）.McNemar Test showed that CKMB and CTNI results from the two kinds of tests had no significant differences（P=0.265,P=0.747）.Conclusion： Myocardial trigeminy test has the ability of prophase diagnosing ACS.Compared with traditional myocardium zymogram,myocardial trigeminy test（CTNI,MYO,CK-MB） has superiority for prophase diagnosing ACS,the two kinds of tests are of good consistency.

作者宋兵王邦宁杜荣美陈大年骆志刚

机构地区安徽医科大学第一附属医院心内科

出处《现代医学》 2010年第6期630-632,共3页 Modern Medical Journal

关键词急性冠脉综合征化验室心肌酶及标志物分析法心梗三联床旁检测法 acute coronary syndrome myocardium zymogram myocardial trigeminy test

分类号 R542.22 [医药卫生—心血管疾病]

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