围术期应激性高血糖发生机制及调控措施研究进展

Advanced mechanisms and control of perioperative stress-induced hyperglycemia

围术期应激性高血糖被认为是围术期应激反应存在和强度的一项指标以及围术期并发症发生和死亡的重要因素.炎性细胞因子参与和胰岛素生物效应通路障碍成为其发生机制研究的新领域;其调控措施的研究很广泛,但各具局限性.围术期应激性高血糖的发生机制和调控措施具有广阔的研究前景.

Perioperative stress-induced hyperglycemia has been identified and used as an index to the existence and intensity of perioperative stress, as well as an important factor for the complication and mortality in perioperation. The participation of cytokines and the barrier of insulin bio-effect pathway have been the new research fields of the mechanism. There are extensive studies done on the control, but the results have limitations. The mechanism and control of perioperative stress-induced hyperglycemia will have spacious research prospects.