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优泌林70/30与优泌乐50治疗2型糖尿病临床观察 被引量:4

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摘要 目的探讨优泌林70/30与优泌乐50治疗2型糖尿病的临床疗效。方法对24例2型糖尿病患者进行为期8周的随机、开放性比较研究。24例2型糖尿病患者被随机分为以优泌林70/30治疗的A组和以优泌乐50治疗的B组。A组采用每日早、晚餐前2次皮下注射优泌林70/30,B组采用每日2次餐前即刻皮下注射优泌乐50治疗方案。比较两组患者7个时点血糖、HbA1c、低血糖事件及依从性。结果 B组三餐后血糖明显低于A组(P<0.05);B组低血糖事件发生次数低于A组(P<0.05)。结论优泌乐50对患者餐后血糖控制更满意,且低血糖发生率减少,依从性良好。
出处 《中国现代医生》 2010年第36期125-125,134,共2页 China Modern Doctor
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  • 1Ceriello A,Cavarape A,Martinelli L, et al.The postprandial state in type 2 diabetes and endothelial dysfunction:effects of insulin aspart [J].Diabete Med,2004,21:171-175.
  • 2McSorley PT,Bell Pw,Jocobsen LV, et al.Twice-daily biphasic human insulin30:adouble-blind cross-over study in people with type 2diabetes [J]. Clin Ther, 2002,24(4):530-539.
  • 3Koro CE,Bowlin SJ,Bourgeois N,et al.Glycemic control from 1988 to 2000 among US adults diagnosed with type 2 diabetes,a preliminary report.Diabetes Care,2004,27:17-20.
  • 4Ceriello A,Esposito K,Piconi L,et al.Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 Diabetic patients.Diabetes,2008,57:1349-1354.
  • 5Mitaa T,Otsukaa A,Azumaa K,et al.Swings in blood glucose levels accelerate atherogenesis in apolipoprotein E-deficient mice.Biochem Biophys Res Commun,2007,358:679-685.
  • 6Desouza C,Salazar H,Cheong B,et al.Association of hypoglycemia and cardiac ischemia:a study based on continuous monitoring.Diabetes Care,2003,26:1485-1489.
  • 7Chang JH,Tseng CF,Wang JY.Hypoglycemia-induced myocardial infarction:an unusual adverse effect of sulfonylureas.Int J Cardiol,2007,115:414-416.
  • 8Holmes G,Galitz L,Hu P,et al.Pharmacokinetics of insulin aspart in obesity,renal impairment or hepatic impairment.Br J Clin Pharmacol,2005,60:469-476.
  • 9De Boer H,Jansen M,Koerts J,et al.Prevention of weight gain in type 2 diabets requiring insulin treatment.Diabetes Obes Metab,2004,6:114-119.
  • 10Pala L,Mannucci E,Dicembrini I,et al.A comparison of mealtime insulin aspart and human insulin in combination with metformin in type 2 diabetes patients.Diabetes Res Clin Pract,2007,78:132-135.

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