摘要
对绿色五氧化二氮在芳烃和氮杂环化合物的硝化反应中的应用进行了详述。五氧化二氮/硝酸体系的硝化能力强,但硝化选择性差,故常用于钝化底物的硝化。五氧化二氮/有机溶剂体系硝化温和,选择性好,主要用于酸敏性和水敏性及含多官能团物质的选择性硝化。同时,对五氧化二氮的合成及放大方法进行了概括。
Nitration of aromatic hydrocarbon and nitrogen heterocyclic by N2O5 was summarized. N2O5/nitric acid system is a very powerful nitration reagent and particularly valuable for the nitration of highly deactivated aromatics. N2O5/organic solvent system is a much milder and more selective nitration reagent, which is suitable for the cases that the substrates or products are sensitive to acid or water, and for region-selective O-nitration. Furthermore, the synthesis and pilot-plant-scale process of N2O5 were also summarized.
出处
《含能材料》
EI
CAS
CSCD
北大核心
2010年第6期611-617,共7页
Chinese Journal of Energetic Materials
关键词
有机化学
五氧化二氮
硝化
绿色
organic chemistry
dinitrogen pentoxide
nitration
clean
