脑白质电导率各向异性及非均质对头皮脑电分布的影响

Effects of White Matter Anisotropic and Inhomogeneous Conductivity on EEG Forward Solutions

脑白质电导率的各向异性和非均质分布是广泛存在的,因此衡量其对脑电正问题计算的影响显得十分重要。而现有研究方法忽略了白质各向异性电导率的非均质性。把白质电导率的非均质划分为四类,分别讨论了各种非均质电导率对脑电正问题的影响。从仿真结果看,认为电导率数值上的偏差是最主要的非均质因素,同时忽略大脑白质电导率非均质会对脑电正问题造成10%左右的计算误差,因而认为非均质的影响是不可忽略的,需要建立能够反映WM非均质且各向异性的电导率模型。

The anisotropic and inhomogeneous distribution of brain white matter（MW）conductivity is widespread,so the measure of its impact on forward problem of EEG is very important.But the existing simulation methods neglected the anisotropy and inhomogenity.First white matter was divided into four categories respectively,and the impact on EEG problems was discussed.From the result of the simulation,we thought that the conductivity bias values on the heterogeneity was the most important factor,while ignoring white matter conductivity heterogeneity would cause about 10% of the calculation error about EEG forward problem.So the impact of conductivity inhomogenity could not be ignored,the inhomogeneous and anisotropic WM conductivity model need to be constructed.