盐酸舍曲林片对2型糖尿病患者抑郁焦虑情绪及糖代谢水平的影响

Effects of sertraline on emotional disorder and glucose metabolism of type 2 diabetes patients

目的了解并探讨盐酸舍曲林片对2型糖尿病患者抑郁焦虑情绪及糖代谢水平的影响。方法将71例2型糖尿病患者随机分为治疗组与对照组,治疗组同时应用盐酸舍曲林片,应用焦虑自评量表(SAS),抑郁自评量表(SDS)及空腹血糖(FPG)、糖化血红蛋白(HbA1c)等代谢指标于治疗前后分别进行抑郁焦虑情绪及糖代谢的测评。结果盐酸舍曲林片对2型糖尿病患者抑郁焦虑情绪改善较对照组显著,且糖代谢更好。结论 2型糖尿病患者多伴有焦虑、抑郁情绪,盐酸舍曲林片可更好地改善抑郁焦虑情绪症状及糖代谢水平。

Objective To determine the depressive and anxiety symptoms in patients with type 2 diabetes and to investigate the effects of sertraline on these symptoms and glucose metabolism.Methods 71 patients with type 2 diabetes were randomly divided into the treated group and the control group.Self-rating anxiety scale（SAS）,self-rating depressive scale（SDS）,and sugar metabolic indicators,such as FPG,HbA1c,were administered in both groups,and all patients were assessed again after receiving sertraline for 3 months.Results The scores of both SAS and SDS,glycometabolism in the sertraline-treated group were significantly improved than those in the control group.Conclusion Anxiety symptoms and depressive symptoms are commonly accompanied in patients with type 2 diabetes,and Sertraline can improve their mood symptoms and glucose metabolism.