东北不同产地五味子药材品质研究

Quality evaluation of Schisandra chinensis at different producing areas in northease china

目的:初步考察东北不同产地五味子药材的品质,为其药材质量标准的制定和规范化种植提供参考。方法:参照药典和相关文献,测定10份不同产地五味子药材的外观性状和水溶性浸出物、灰分和挥发油含量,并以HPLC测定木脂素类成分含量。结果:东北不同产地五味子药材中总灰分含量≤7.0%,酸不溶性灰分含量≤1.0%,水溶性浸出物含量≥45.0%,同时这10份药材中五味子醇甲含量则均符合我国2010年版药典规定。结论:东北不同产地五味子药材的外观性状和内在品质均存在差异,因此建立科学全面的质量标准对保证五味子药材品质具有重要意义。

Objective： To investigate the quality of Schisandra chinensis,and thus provide the useful reference data for its quality standard establishment and standardized cultivation.Method： Base on the Chinese Pharmacopoeia and literature relating to S.chinensis,the appearance,water-soluble extractive,total ash,acid-insoluble ash and volatile oil of 10 S.chinensis sampes collacted from different producing sites in northease China were studied or determined,and the contents of major active lingans were measured by HPLC.Result： The content of total ash and acid-insoluble ash in S.chinensis was less than 7.0%,1.0%,respectively.The contents of water-soluble extractive were higher than 45.0%.HPLC analyses showed that the content of schisandrol A was higher than 0.40%.All these results in accordance with the requirements of Chinese Pharmacopoeia were published in 2010.Conclusion： The differences of the appearance and the internal quality are different for the samples collected from different areas.And the establishment of a scientific and comprehensive quality standard system will be very important role in ensuring the quality of S.chinensis.