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Snail和IKKβ在非小细胞肺癌组织中的表达及意义

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摘要 目的探讨Snail和IKKβ在非小细胞肺癌(NSCLC)组织中的表达及临床意义。方法应用免疫组织化学方法检测45例NSCLC组织中Snail和IKKβ蛋白表达情况。结果肺癌组织标本中,Snail和IKK的阳性表达率分别为68.9%、57.8%。Snail高表达与肺癌分化程度相关,IKKβ高表达与肺癌淋巴结转移相关。Snail蛋白的表达之间存在显著正相关。结论 NSCLC中存在Snail和lKKβ蛋白的高表达。NSCLC组织中Snail和IKKβ表达的上调,对肿瘤的发生、发展起着重要作用。
作者 田宏
出处 《中国实用医药》 2010年第36期131-132,共2页 China Practical Medicine
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参考文献3

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