ADA、IFN-γ和TNF-α联合检测对结核性胸腔积液与恶性肿瘤胸腔积液的鉴别诊断价值

The differential diagnosis value of ADA,IFN-γ and TNF-α combined detection for tuberculous pleural effusion and malignant pleural effusion

目的 探讨ADA IFN-γ TNF-α测定对结核性胸腔积液与恶性肿瘤胸腔积液的鉴别诊断价值.方法 对100例结核性胸腔积液和50例恶性胸腔积液标本进行ADA IFN-γ TNF-α联合检测.结果 结核性胸腔积液ADA（55.6±13.5）IFN-γ（101.5±30.5）TNF-α（72.2±20.2）,恶性胸腔积液ADA（12.5±4.0） IFN-γ（28.3±8.1） TNF-α（22.5±6.5）,结核性胸腔积液ADA IFN-γ TNF-α水平高于恶性胸腔积液,有极显著意义（P＜0.01）.结论 ADA IFN-γ TNF-α联合测定对结核性胸腔积液与恶性胸腔积液的临床鉴别诊断具有重要意义.

Objective Discussion of ADA, IFN -γ, determination of TNF- α on tuberculous p]eural effusion and malignant pteural effusiion of differential diagnosis. Methods 100 cases of tuberculous pleural effusion and 50 cases of malignant pIeural effusion s rvecimcns for ADA, IFN, TNFwas made joint detection. Results Tuberculous pleural effusion ADA （55.6 ± 13.5） IFN - γ（ 101.5 ± 30.5） TNF - α （72. 2 ±20. 2）, malignant pleural effusion ADA （12.5 ±4.0） IFN - γ（28.3 ±8.1） TNF - α （22.5 ±6.5）, tuberculous pleural effusion level higher than the ADA IFN - TTNF- α malignant pleural effusion, have very significant （P〈 0.01）. Conclusions ADA IFN - γ TNF- α on tuberculous pleura1 effusion and malignant pleuml effusion is of great significance in the differential diagnosis.