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高尔基体糖蛋白-73异常表达与肝癌诊断 被引量：4

Abnormal expression of golgi glycoprotein 73 and diagnosis of hepatocellular carcinoma
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摘要 高尔基体糖蛋白-73(GP73)为经糖基化修饰的膜蛋白,肝癌患者中GP73上调表达。外周血中较高水平的GP73与肝癌相关,在肝癌早期诊断方面,GP73优于AFP,是一具有较高临床诊断价值的新的肝癌标志物。 Golgi glycoprotein-73（GP73） is a fucosylated glycosylation and up-regulated in hepatocellular carcinoma（HCC）.Higher levels of GP73 can be found in the serum of patients with HCC.GP73 could be better than AFP for the diagnosis of early HCC and should be a new tumor marker for HCC diagnosis.
作者 赛文莉 姚登福
机构地区 南通大学附属医院临床医学研究中心
出处 《胃肠病学和肝病学杂志》 CAS 2011年第1期8-10,共3页 Chinese Journal of Gastroenterology and Hepatology
基金 南通市社会发展项目(S2009038) 南通大学附属医院项目(TDFY09003)
关键词 肝细胞癌 高尔基体糖蛋白-73 诊断 Hepatocellular carcinoma Golgi glycoprotein 73 Diagnosis
分类号 R735.7 [医药卫生—肿瘤]
  • 相关文献

参考文献9

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二级参考文献16

  • 1Hubert E Blum.Hepatocellular carcinoma: Therapy and prevention[J].World Journal of Gastroenterology,2005,11(47):7391-7400. 被引量：27
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共引文献201

同被引文献24

  • 1Thomas Gbel,Sonja Vorderwülbecke,Katarzyna Hauck,Holger Fey,Dieter Hussinger,Andreas Erhardt.New multi protein patterns differentiate liver fibrosis stages and hepatocellular carcinoma in chronic hepatitis C serum samples[J].World Journal of Gastroenterology,2006,12(47):7604-7612. 被引量：21
  • 2Joachim Lupberger,Eberhard Hildt.Hepatitis B virus-induced oncogenesis[J].World Journal of Gastroenterology,2007,13(1):74-81. 被引量：57
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  • 10毛一雷,杨华瑜,徐海峰,桑新亭,卢欣,杨志英,张锦春,钟守先,黄洁夫,张宏冰.新的肝癌血清标记物GP73在肝癌诊断中的初步研究[J].中华医学杂志,2008,88(14):948-951. 被引量：132

引证文献4

二级引证文献11

胃肠病学和肝病学杂志
2011年 第1期

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