三氯化稀土催化下二乙氧基缩苯乙酮与乙酰氯的反应——合成1,3,5-三芳基苯的新方法

The Reaction of Acetophenone Diethyl Ketals and Acetyl Chloride Promoted by Lanthanide Trichlorides——A Novel Method for the Synthesis of 1,3,5 - Triarylbenzenes

报道催化量的三氯化钐存在下,乙酰氯与二乙氧基缩苯乙酮反应,高产率地得到1,3,5-三苯基苯.采用不同的溶剂及不同的稀土氯化物该反应均能顺利进行.此方法是一种合成1,3,5-三芳基苯类化合物的方便和有效的方法.文中对反应机理进行了讨论.

In the presence of catalytic amounts of samarium trichloride, acetophenone diethyl ketals reacted with acetyl chloride to give 1,3,5 - triarylbenzenes in high yields. This reaction proceeds smoothly in a variety of solvents with various lanthanide trichlorides, providing a novel method for the synthesis of 1,3,5- triarylbenzene. A reasonable mechanism for this reaction is suggested.