摘要
Methods for separating 1-(2,4-Dichlorophenyl) 4, 4-dimethyl 1-2(1,2,4-triazol-l-yl) 1-penten-3-ol isomers and D,L-tryptophan enantiomers using HPTLC and TLC were investigated. The effects on Separation made by different nonchiral mobile phase, chiral mobile phase and two different shapes of plates were studied. Useful separation was obtained forstereoisomers, and the resolution of D, L-tryptophan was good by using chiral mobile phase additive(D-quinia).
Methods for separating 1-(2,4-Dichlorophenyl) 4, 4-dimethyl 1-2(1,2,4-triazol-l-yl) 1-penten-3-ol isomers and D,L-tryptophan enantiomers using HPTLC and TLC were investigated. The effects on Separation made by different nonchiral mobile phase, chiral mobile phase and two different shapes of plates were studied. Useful separation was obtained forstereoisomers, and the resolution of D, L-tryptophan was good by using chiral mobile phase additive(D-quinia).
出处
《化学研究与应用》
CAS
CSCD
1999年第5期552-554,共3页
Chemical Research and Application
关键词
薄层色谱
环糊精
光学异构体
手性
流动相
拆分
thin layer chromatography, cyclodextrin, optical isomer, chiral mobile phase
