妊娠期女性阴道微生态状况的分析

Analysis of the vaginal microecology in pregnant women

目的分析妊娠期女性阴道微生态状况。方法妊娠妇女91例分为早孕期(A组,33例),中孕期(B组,30例)和晚孕期(C组,28例)3组,以阴道pH值、阴道脱落细胞致密核指数(KI)、阴道菌群三项指标对阴道清洁度和阴道微生态进行评价。结果 A、B、C三组KI分别为(89.94±3.29)%、(89.30±2.90)%、(89.93±2.62)%;乳酸杆菌优势率为87.88%、83.33%、75.00%;阴道pH值为(3.80±0.39)、(3.78±0.31)、(3.78±0.34);三项指标组间差异均无统计学意义。91例妊娠期妇女阴道pH值与KI呈负相关(P<0.01)。结论不同妊娠期妇女阴道KI、乳酸杆菌优势率、阴道pH值相似;pH值减低,KI及乳酸杆菌优势率增高。

Objective To analyze the vaginal microecology and characteristics of women during different pregnant periods.Methods Ninety-one pregnant women were divided into three groups of early pregnancy（group A,33 cases）,middle pregnancy（group B,30 cases） and late pregnancy（group C,28 cases）.Vaginal pH,karyophknotic index（KI） and vaginal microbial population were evaluated.Results The KI of groups of A,B and C were （89.94±3.29）%,（89.30±2.90）% and （89.93±2.62）%,respectively.The advantage rates of bacillus acidi lactici were 87.88%,83.33% and 75.00%,respectively.The vaginal pH values of groups of A,B and C were （3.80±0.39）,（3.78±0.31） and （3.78±0.34）,respectively.The above three criteria were not significantly different among groups of A,B and C.The vaginal pH and KI in 91 pregnant women were negatively correlated（r=-0.604,P0.01）.Conclusion There is no significant difference of vaginal KI,advantage rate of bacillus acidi lactici and vaginal pH in women during diffenent pregnant periods.The vaginal pH decreases,whereas KI and advantage rate of bacillus acidi lactici increase.