正交函数分光光度法测定安痛定注射液中氨基比林的含量

Determination of the Content of Aminopyrine in Antongding Injection by Orthogonal Function Spectrophotometry

本文采用正交函数分光光度法测定安痛定注射液中氨基比林的含量。６ 个测试点波长分别为２５７，２６１，２６５，２６９，２７３，２７７ ｎｍ 。氨基比林浓度在５～２５ μｇ·ｍ Ｌ－ １ 范围内与Ｐ２ 呈良好的线性关系，回归方程为Ｐ２＝ ０．０１８－ ０．０３２ ９ｃ，ｒ＝ ０．９９９ ９。平均回收率为１００．３％ ，ＲＳＤ为０．４０％ 。本法与河北省地方标准［１］比较，结果无显著性差异。

Determination of the content of aminopyrine in the antongding injection by orthogonal function spectrophotometry was reported in this paper.The six wavelengths for the determination are 257,261,265,269,273 and 277 nm.The concentration of aminopyrine in the range of 5—25 μg·mL -1 is in a good linear relation to P 2,and the regression equation is P 2=+0 018-0 032 9c,r=0 999 9.The average recovery and relative standard deviation are 100 3% and 0 40%,respectively.On the basis of the data observed it is concluded that this method shows no obvious difference as compared with Hebei province pharmacy regulation.