急性肾功能衰竭临床和预后分析

Clinical Analysis of Acute Renal Failure and Its Prognosis

目的分析急性肾功能衰竭(ARF)的病因、转归,并探讨其发生的危险因素。方法回顾性分析我院2007—2009年收治的114例ARF患者的临床资料。结果 ARF的病因中排前3位的分别是急性药物性间质性肾炎(占15.8%)、原发性肾小球疾病(占14.0%)和肾后梗阻(占13.1%)。114例ARF患者中治愈55例(48.2%),好转42例(36.8%),死亡17例(14.9%)。死亡的患者中以伴有多脏器衰竭、高龄、肿瘤的患者为主。结论 ARF的病因很多,内科中最常见的病因仍然是急性药物性间质性肾炎,应当引起医务人员的注意;北方地区结石的发病率高,引起梗阻性ARF的发病率高;ARF的病死率与是否伴有多脏器衰竭、年龄及原发病有关。

Objective To analyze the etiology and turnover of ARF and to explore its risk factors.Methods Analyze retrospectively the clinical data of 114 patients with acute renal failure admitted in our hospital from January 2007 to December 2009.Results The top three etiologies accounted for acute renal failure were drug-induced acute interstitial nephritis（15.8%）,primary glomerular disease（14.0%） and renal obstruction（13.1%）.Among the 114 patients with ARF,55 cases were cured（48.2%）,42 cases were improved（36.8%） and 17 cases were died（14.9%）.The death cases were mainly associated with multiple organ failure,higher age and carcinoma.Conclusion There are many causes of ARF,the most common cause in internal medicine is still drug-induced acute interstitial nephritis,which should arouse the attention of medical personnel;incidence of stones in north is high,causing high incidence of obstructive ARF;ARF mortality is associated with multiple organ failure,age and primary disease.