艾油膏治疗慢性浅表溃疡临床观察

Therapeutical efficacy of the olaum balsmiferi in chronic superficial ulceration

目的:检测艾油的理化、毒理、药理特性,探讨艾油膏治疗慢性浅表溃疡的临床疗效。方法:用实验方法和仪器对艾油烧伤膏的理化、药理、毒理特性进行检测。用艾油膏对30例慢性浅表溃疡患者进行治疗观察,与使用聚维酮碘治疗的30例既往慢性浅表溃疡患者进行疗效对比。结果:艾油膏有良好的止痛效果,痛阈率提高49.27%,半数致死剂量(LD50)为5.95g/kg,95%,无过敏刺激性。两组患者创面细菌培养及抗生素使用情况,差异无统计学意义(P>0.05);创面愈合时间和创面覆盖现状,差异均有统计学意义(P<0.05)。结论:艾油具有良好的理化特性,患者创面愈合快,镇痛效果好。

Objective：To determine the physicochemistry,toxicology and pharmacology of olaum balsferi,study the therapeutical efficacy of the olaum balsmiferi in treatment of chronic superficial ulceration.Methods：Determined the phycicochemisty,pharmacology,toxicology of the olaum balsmiferi by the experiments and instvuments.Used the olaum balsmferi to treatment and observed the efficacy for chronic superficial ulceration of 30 cases,and compared to the other 30 cases with povidone iodine.Results：The olaum balsmferi could obviously relieve the pain of the burn wound,highten the rate of threshold of pain.LD50 was 5.95 g/kg 95%,there was no irritation and hypersencitivity.There was no difference in the therapeutical efficacy between the two groups（P0.05）,while there was marked difference in healing period of time and the states between the two groups（P0.05）.Conclusion：The olaum balsmferi has a good quality of phycicochemisty,healing time is shorter,has efficacy of reliving pain.