云南大红山铜矿区成年居民铜、铁、锌血清水平和膳食摄入量

Serum levels and dietary intakes of copper, iron, and zinc among adult residents in Dahongshan copper mine area of Yunnan Province

目的 了解云南大红山铜矿成年居民铜、铁、锌的血清水平和膳食摄入量.方法 在大红山矿区随机抽取180名成年居民,采用原子吸收分光光度法检测血清铜、铁、锌水平.从180人中随机抽取60人,采刚化学分析法调查膳食铜、铁、锌摄入量.结果 171人的血清铜、铁、锌水平分别为（0.90±0.18）、（1.25±0.93）、（0.75±0.28）mg/L,血清铜和铁呈显著负相关（r=-0.26,P＜0.001）.血清铜与年龄呈显著正相关（r=0.25,P＜0.001）,女性血清铜水平明显高于男性（P=0.011）.60人的膳食铜、铁、锌摄入量分别为（1.74±1.09）、（16.29±10.73）、（7.56±3.38）mg/d,女性均明显低于男性（P＜0.05）.血清铜、铁、锌水平和膳食摄入量均存在地区差异.结论 云南大红山矿区成年居民血清铜、铁水平均正常,血清锌水平偏低.铜、铁、锌的膳食摄入量均未超过可耐受最高摄人量,且部分人摄入量偏低.

Objective To investigate the serum levels and dietary intakes of copper, iron, and zinc among adult residents in Dahongshan copper mine area of Yunnan Province in China. Methods Serum levels of copper, iron, and zinc were measured by atomic absorption spectrometry among 180 subjects collected randomly from Dahongshan mine area, among which 171 samples were valid. Dietary intakes of copper, iron, and zinc of 60adults collected randomly from these 180 subjects were detected by chemical analysis. Results Serum levels of copper, iron, and zinc concentrations of 171 valid samples were （0.90±0.18）, （1.25±0.93） , and （0.75±0. 28） mg/L, respectively. Serum copper was negatively correlated with serum iron （r = - 0. 26, P 〈 0. 001）. Serum copper was positively correlated with age （r = 0. 25, P 〈 0. 001）. Females had significantly higher serum copper than males （P=0.011）. The dietary intakes of copper, iron, and zinc among these 60 subjects were （1.74±1.09）,（16.29±10.73）, and （7.56±3.38） mg/d, respectively, in which females had significantly lower dietary intakes than nales （all P 〈 0. 05）. Significant regional differences were observed both in serum levels and dietary intakes of copper, iron, and zinc. Conclusions The average serum levels of copper and iron are normal among adult residents in Dahongshan copper mine area, while the average serum zinc level is low. Dietary intakes of these three minerals do not exceed tolerable upper intake levels, and are low in some subjects.