肝硬化合并自发性细菌性腹膜炎38例临床分析

Clinical analysis of 38 cases of cirrhosis plus spontaneity bacterial peritonitis

目的：提高对肝硬化合并自发性细菌性腹膜炎（SBP）临床诊治水平的认识.方法：对38例SBP患者的临床表现、治疗及转归进行回顾性分析.结果：许多SBP患者临床表现不典型,诊断需要依靠腹水中多形核白细胞计数和细菌培养,Child-Pugh分级和凝血酶原活动度（PTA）均与SBP预后具有相关性,Child-Pugh分级评分越高,预后越差 PTA水平越低,预后越差.结论：SBP的临床诊断应综合考虑,早期诊断及积极治疗是提高SBP临床治愈率的关键.

Objective： To improve the understanding of the clinical diagnosis and treatment of cirrhosis plus spontaneity bacterial peritonitis. Methods： To analyze the clinical manifestations and treatment of 38 cases of SBP patient. Results： The clinical manifestations of lots of SBP patient were atypical, the polymorphonuclear leukocyte count and bacterial culture were depended by diagnosis, child-Pugh classification and prothrombin activity （PTA） were related with the prognosis of SBP, the child-Pugh classification was higher, the prognosis was worse; The levels of PTA was lower, the prognosis was worse. Conclusion： To improve the clinical cure rate of the key SBP was early diagnosis and aggressive treatment.