急性冠脉综合征BNP与hs-CRP水平的相关性分析

Relevance analysis of acute coronary artery and syndrome BNP and hs-CRP level

目的：探讨急性冠状动脉综合征（ACS）患者血清脑利钠肽（BNP）与高敏C-反应蛋白（hs-CRP）指标的相关性及其在ACS患者危险中的临床意义.方法：ACS患者52例,选择年龄、性别等与之相匹配稳定型心绞痛患者及其它疾病患者各40例做对照.酶联免疫吸附法测定血清BNP浓度,免疫比浊法测定hs-CRP浓度.结果：急性心肌梗死组和不稳定型心绞痛组患者的血清BNP浓度均明显高于稳定型心绞痛和其它疾病组患者,差异均具有统计学意义（P＜0.01和P＜0.05） 在ACS组中,BNP与hs-CRP具有相关性（P＜0.05）.结论：血清BNP浓度在ACS患者中明显升高,可作为辅助诊断指标之一.ACS患者血清BNP浓度升高程度与同期测定的血清hs-CRP呈显著正相关.

Objective： Probe into acute coronary artery syndrome （ACS） patient serum brain favourable sodium peptide （BNP） and Gao Min C - response albumen relevance of index and in clinical meaning of being dangerous, patient of ACS. Methods： 52 ACS patients, Choose age, sex,etc, match it getting steady angina pectoris patient and other disease patient respectively 40 contrast of making. Enzyme unites the immune adsorption method and determines serum BNP density, The immunity determines hs-CRP density more than the turbid law. Result： Acute myocardium infarction group and getting unstable angina pectoris group density, BNP of serum, of patient higher than getting steady angina pectoris and other patient, group of disease, obviously, the difference has a statistics meaning （P〈0.01 and P〈0.05）. Conclusion： Serum BNP density obviously rises among ACS patient, can be as assisting diagnosing one of the indexes. Density, BNP of serum, patient of ACS, rise intensity with serum that determine in the same term hs-CRP the prominent positive correlation.