摘要
目的：探讨联合应用促动力药吗丁啉慢性咽炎咽异感证的疗效问题.方法：将82例表现为慢性咽炎的胃食管反流病患者,随机分为治疗组42例（艾索美拉唑联合应用吗丁啉）和对照组40（单纯使用艾索美拉唑）治疗.比较治疗前后慢性咽炎、咽异感症状改变情况.结果：治疗组42例患者与对照组40例患者的基本情况无显著差异性 采取艾索美拉唑联合应用促动力药吗丁啉,治疗慢性咽炎咽异感证的疗效比单纯使用艾索美拉唑的疗效好.两者有效率分别为71.43%和57.5%,比较结果具有显著差异性（P＜0.05）,具有统计学意义.结论：艾索美拉唑联合应用吗丁啉,既能发挥质子泵抑制剂和促动力药物对胃酸分泌的长效抑制作用,又能缓解反流液对咽喉部粘膜及食道的刺激,能达到标本兼治的治疗目的,值得在临床治疗中推广使用.
Objective： To investigate the effect of treating chronic pharyngitis with motilium. Methods： 82 cases of gastroesoph -ageal reflux of chronic pharyngitis, randomly divide into treatment group 42 cases （using esomeprazole and motilium） and control group 40 cases （using esomeprazole）. Compared with change the situation of chronic pharyngitis before and after treatment. Results： Two groups have no significant difference; the effect of treatment group was better than control group. The total effective rate were 71.43% and 57.5%, the results of comparsion has significant difference （P〈0.05）. Conclusion： Using esomeprazole and motilium, not only inhibit gastric acid, but also mitigation solution on the throat reflux and esophageal mucosal stimulation, to achieve objective of treating the symptoms, was worth being applied.
出处
《中医临床研究》
2010年第24期104-105,共2页
Clinical Journal Of Chinese Medicine
关键词
吗丁啉
慢性咽炎
临床
Motilium
Chronic pharyngitis
Clinical
