肿瘤坏死因子-α与妊娠期糖尿病

Tumor Necrosis Factor-α and Gestational Diabetes Mellitus

妊娠期糖尿病（GDM）是指妊娠期间才发现的任何程度的糖耐量异常,是糖尿病分类中的一种独立类型.GDM直接威胁着孕妇、胎儿和新生儿的健康,容易导致巨大儿、羊水过多、妊娠高血压和新生儿并发症等.笔者从肿瘤坏死因子-α、胰岛素抵抗和胰岛β细胞分泌缺陷等方面探讨了GDM的发病机制.

Gestational diabetes mellitus is impaired glucose tolerance on gestational, is a independent type on classification of diabetes. GDM lead to health of pregnant women, fetuses and newborns, lead to complications of great children, polyhydramnios, and pregnancy- induced hypertension and neonatal. To investigate the pathogenesis of GDM from TNF-α, IR and B-cell secretion.