头孢布烯与头孢三嗪序贯治疗中重度下呼吸道感染临床观察

Clinical Observation of Step down Therapyof Ceftibuten and Ceftriaxone in the Treatmentof Medium or Serious Lower Respiratory Infection

比较头孢三嗪、头孢布烯序贯疗法与单用头孢三嗪静脉治疗３４ 例中、重度下呼吸道感染的临床疗效和治疗费用。结果显示：序贯组（Ａ 组） 临床总有效率为８８ ．２４ ％ ，单用头孢三嗪组（Ｂ 组） 临床总有效率为８８ ．２４ ％ ，２ 组间无显著性差异（ Ｐ＞ ０ ．０５） ；总医疗费用序贯组为（２ １６５ ．３６ ±５３９ ．７８） 元，单用头孢三嗪组为（２ ６９８ ．１４ ±７６５ ．８４） 元，２组间具有显著性差异（ Ｐ＜ ０ ．０５） 。结果提示序贯疗法与单独静脉治疗具有相同的临床疗效，但显著降低了医疗费用。

The purpose of this study was to compare the curative effect and the medicalexpenditure of sequentialtherapy with intravenous infusion of ceftriaxone followed by oralceftibuten and intravenous infusion of ceftriaxone alone in treatment of 34 patients with medium or serious lower respiratory infection . The resultsshowed that :The over alleffective rate ofthe sequential group and theintravenous infusion alone group was 88 .24 % ,there was no difference between two group ( P> 0 .05) ;the total medical expenditure ofthe sequential group and the intravenous infusion alone group was (2 165 .36 ± 539 .78) yuan and (2 698 .14 ±765 .84) yuan respectively ,there was statistical difference between two groups ( P< 0 .05) .Sequentialtherapy and intravenousinfusion alone have similar clinical efficacy .But the sequential therapy compared with intravenous infusion alone reduced medical expenditure significantly .