摘要
研究8-MOP与ATRA单独及联合应用对Mc3细胞的生长抑制作用。方法:用IC30的8-MOP、ATRA以及二者联合作用于Mc3细胞,用细胞计数法测定细胞生长曲线。结果:细胞倍增时间分别为:对照组29.7h;8-MOP组39.9h;ATRA组73.4h;联合用药组56.7h。结论:8-MOP、ATRA以及二者联合应用能使Mc3细胞的倍增时间延长,生长速度减慢,表明8-MOP和ATRA可抑制Mc3细胞生长。
To study the growt h in-hibitory effects of 8-MOP or/ahd ATRA on Mc3cells. Methods: Mc3 cells were treated with 8-MOP or/and ATRA at the dose of IC30, growthcurves were obtained by cell counting. Results:The doubling time was 29. 7 h, 39. 9 h, 73. 4 hand 56. 7 h for control, 8-MOP, ATRA and 8-MOP with ATRA group respectively. Conclu-sha: 8-MOP or/and ATRA may inhibit Mc3cells growth.
出处
《实用口腔医学杂志》
CAS
CSCD
北大核心
1999年第6期459-460,共2页
Journal of Practical Stomatology
基金
国家自然科学基金!39370740