8-MOP、ATRA以及二者联合应用对Mc3细胞生长的抑制作用

Growth Inhibitory Effects of 8-MOP or/and ATRA on Mc3 Cells

研究8-MOP与ATRA单独及联合应用对Mc3细胞的生长抑制作用。方法：用IC30的8－MOP、ATRA以及二者联合作用于Mc3细胞，用细胞计数法测定细胞生长曲线。结果：细胞倍增时间分别为：对照组29．7h；8－MOP组39．9h；ATRA组73．4h；联合用药组56．7h。结论：8－MOP、ATRA以及二者联合应用能使Mc3细胞的倍增时间延长，生长速度减慢，表明8－MOP和ATRA可抑制Mc3细胞生长。

To study the growt h in-hibitory effects of 8-MOP or/ahd ATRA on Mc3cells. Methods: Mc3 cells were treated with 8-MOP or/and ATRA at the dose of IC30, growthcurves were obtained by cell counting. Results:The doubling time was 29. 7 h, 39. 9 h, 73. 4 hand 56. 7 h for control, 8-MOP, ATRA and 8-MOP with ATRA group respectively. Conclu-sha: 8-MOP or/and ATRA may inhibit Mc3cells growth.